Glycofecttm Biodegradable Transfection Reagent for Primary Cells

Primary Dermal Fibroblasts (left) transfected with a leading lipid-based reagent (center) and with Glycofect Transfection Reagent (right). Glycofect is a new DNA carrier that elicits low cytotoxic response coupled with high delivery efficiency and transgene expression. Glycofect is a superior reagent for primary cell transfection as compared to leading lipid- and polycation-based products.  Learn more about Glycofect.

ATTENTION:  If you are investigating the following cell types you should contact us today for a free evaluation of Glycofect.  Glycofect has been shown to provide increased efficiency and lower toxicity than other reagents in these cell types, and more are being added weekly:

> Glioblastoma

> Cortical Neurons

> NIH-3T3

> MCF-7

> HASM

> HDFn

> C2C12 Myoblast

> HEK293

Glycofect is a cationic carbohydrate-containing synthetic polymer based on the poly-glycoamidoamine (PGAA) polymer library developed by Dr. Theresa M. Reineke et al.  These polymers contain linkages that hydrolyse upon endocytosis, thereby increasing plasmid delivery and reducing toxicity.  If lower toxicity and higher cell survival rate are important for your investigations or therapy development you should contact us today for a consultation and free evaluation of Glycofect Transfection Reagent.